The predictive effect of primary tumour location in the treatment of metastatic colorectal cancer: a Canadian consensus statement

A.B.K. Abrahao, S. Karim, B. Colwell, S. Berry, J. Biagi


In recently published data, the predictive value of primary tumour location for the treatment of metastatic colorectal cancer with available biologic therapies has been explored. Recognizing the potential effect of those data on clinical practice, we convened a meeting of Canadian experts who treat metastatic colorectal cancer to develop a set of national, evidence-based treatment guidelines based on primary tumour location. This report summarizes the relevant evidence and presents the consensus recommendations of those experts.



Metastatic colorectal cancer; primary tumour location; tumour side; prognostic value; predictive value; egfr monoclonal antibodies; RAS wild-type; consensus statements

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ISSN: 1198-0052 (Print) ISSN: 1718-7729 (Online)