The importance of a satisfactory biopsy for the diagnosis of lung cancer in the era of personalized treatment

  • L.M. Ofiara McGill University
  • A. Navasakulpong
  • N. Ezer
  • A.V. Gonzalez

Abstract

Advances in molecular biology are improving the understanding of lung cancer and changing the approach to treatment. A satisfactory biopsy that allows for histologic characterization and mutation analysis is becoming increasingly important. Most patients with lung cancer are diagnosed at an advanced stage, and diagnosis is often based on a small biopsy or cytology specimen. Here, we review the techniques available for making a diagnosis of lung cancer, including bronchoscopy, ultrasound-guided bronchoscopy, mediastinoscopy, transthoracic needle aspiration, thoracentesis, and medical thoracoscopy. We also discuss the indications, complications, and tissue yields of those techniques, especially as they pertain to testing for molecular markers.

Author Biography

L.M. Ofiara, McGill University

Division of Respiratory Medicine

Department of meical Oncology

How to Cite
Ofiara, L., Navasakulpong, A., Ezer, N., & Gonzalez, A. (1). The importance of a satisfactory biopsy for the diagnosis of lung cancer in the era of personalized treatment. Current Oncology, 19, S16-23. https://doi.org/10.3747/co.19.1062