Localized synchronous squamous cell carcinomas of the esophagus and hypopharynx treated with definitive concurrent chemoradiotherapy with a unified radiotherapy plan

  • J.B. Wallach Montefiore Medical Center and the Albert Einstein College of Medicine
  • M.M. Rosenstein Montefiore Medical Center and the Albert Einstein College of Medicine
  • S. Kalnicki Montefiore Medical Center and the Albert Einstein College of Medicine
Keywords: Synchronous squamous cell carcinomas, Esophageal cancer, Hypopharyngeal cancer, Chemotherapy, Radiotherapy, Field cancerization

Abstract

Because of common risk factors, synchronous squamous cell carcinomas of the esophagus and head and neck are common, and their concurrent presence can significantly complicate disease eradication and survival. Here, we report the case of a patient with a history of extensive tobacco and alcohol use who was diagnosed with a localized thoracic esophageal squamous cell carcinoma, and in whom positron-emission tomography–computed tomography discovered a nearby asymptomatic localized hypopharyngeal focus that was confirmed by biopsy to also be malignant. He was treated with definitive concurrent chemoradiotherapy in a single unified radiotherapy plan, with surgery reserved for salvage treatment. He currently remains in remission without a need for surgical salvage. However, significant concern remains for both treatment failure and development of another primary because of “field cancerization.”
Published
2014-01-14
How to Cite
Wallach, J., Rosenstein, M., & Kalnicki, S. (2014). Localized synchronous squamous cell carcinomas of the esophagus and hypopharynx treated with definitive concurrent chemoradiotherapy with a unified radiotherapy plan. Current Oncology, 21(2), e354-e357. https://doi.org/10.3747/co.21.1844
Section
Case Report