First case of sternum replacement with a bioceramic prosthesis after radio-induced sarcoma

F. Bertin, E. Deluche, J. Tricard, A. Piccardo, E. Denes



To date, no “gold standard” technique has been developed for sternum replacement in cases of radioinduced sarcoma, which is a rare and aggressive disease. Current techniques rely on metallic prostheses, meshes, or bone grafts—procedures that that are associated with several complications. We therefore tried a new solution that might simplify and optimize this surgery.


We used a porous alumina ceramic prosthesis (Ceramil: i.ceram, Limoges, France) that has several interesting characteristics, such as osseointegration, biocompatibility, radiolucency, and high mechanical strength.


We report the first case of sternal replacement surgery involving the implantation of a ceramic prosthesis after radio-induced sternal sarcoma. In 2005, a 54-year-old woman was diagnosed with local breast cancer for which she underwent all appropriate treatment. Ten years later, she developed radio-induced sarcoma of the sternum. A complete sternal replacement was performed on 24 April 2015, with no postoperative complications. Imaging by 18F-flurodeoxyglucose positron-emission tomography–computed tomography performed 26 months after the surgery showed no local recurrence. The patient seems to have fully recovered and has resumed normal activity.


This new technique is promising. For the first time, we highlight the feasibility, safety, and efficacy of sternal replacement using a porous alumina ceramic prosthesis.


Breast cancer; sarcoma; radio-induced disease; bioceramic prostheses; sternum replacement

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ISSN: 1198-0052 (Print) ISSN: 1718-7729 (Online)