Association between known risk factors and colorectal cancer risk among Indigenous people participating in the Ontario Familial Colon Cancer Registry

  • S. Jamal Ontario Health (Cancer Care Ontario)
  • A.J. Sheppard Ontario Health (Cancer Care Ontario), Dalla Lana School of Public Health, University of Toronto
  • M. Cotterchio Ontario Health (Cancer Care Ontario), Dalla Lana School of Public Health, University of Toronto
  • S. Gallinger Lunenfeld–Tanenbaum Research Institute, Sinai Health System, University Health Network
Keywords: Indigenous health, cancer prevention,

Abstract

Introduction: Colorectal cancer is one of the most common cancers in Ontario and poses a high burden among many Indigenous populations. There are two aims for this short communication: (1) highlight colorectal risk factor findings from a population-based case-control study, (2) highlight trends and challenges of colorectal cancer research among Indigenous populations in Ontario.

Methods: Prevalence of cigarette smoking, obesity, diet  and family history of colorectal cancer were estimated using the Indigenous identifier in the Ontario Familial Colon Cancer Registry (OFCCR) from 1999-2007 and then compared using age-adjusted odds ratio (with 95% confidence intervals) between cases and controls.

Results: There were 66 Indigenous cases and 23 Indigenous controls. Cigarette smoking and obesity were higher in cases, but not statistically significant.

Discussion and Conclusions: Findings were consistent with previous literature among Indigenous populations. Colorectal cancer risk factor and screening uptake information is limited among Indigenous populations; however, self-reported screening data suggest low colorectal screening uptake. Small sample size and poor Indigenous identification questions make it challenging to comprehensively understand cancer risk factors and burden in these populations.


Author Biography

S. Gallinger, Lunenfeld–Tanenbaum Research Institute, Sinai Health System, University Health Network

Department of Surgery

Published
2020-04-17
How to Cite
Jamal, S., Sheppard, A., Cotterchio, M., & Gallinger, S. (2020). Association between known risk factors and colorectal cancer risk among Indigenous people participating in the Ontario Familial Colon Cancer Registry. Current Oncology, 27(4). https://doi.org/10.3747/co.27.6039
Section
Short Communication