Primary central nervous system T-cell lymphoma in AIDS patients: case report and literature review

  • S. Latta Saint Joseph Hospital/University of Illinois
  • Z.W. Myint
  • B. Jallad
  • T. Hamdi
  • M.N. Alhosaini
  • D.V. Kumar
  • F. Kheir

Abstract

According to the published data, most primary central nervous system lymphomas (PCNSLs) are B-cell lymphomas; primary T-cell lymphomas are rare. In a search of the MEDLINE database, we found only 6 cases of primary T-cell PCNSL. Here, we present the case of a 43-year-old man with AIDS, not on highly active antiretroviral therapy, who presented with focal neurologic symptoms and was found on magnetic resonance imaging to have multiple brain lesions. A biopsy showed T-cell lymphoma, and the patient was subsequently treated with whole-brain radiation, to marked clinical response. Reported cases from the literature of primary T-cell PCNSL in AIDS patients are summarized in this review.


How to Cite
Latta, S., Myint, Z., Jallad, B., Hamdi, T., Alhosaini, M., Kumar, D., & Kheir, F. (1). Primary central nervous system T-cell lymphoma in AIDS patients: case report and literature review. Current Oncology, 17(5), 63-66. https://doi.org/10.3747/co.v17i5.621
Section
Case Report