Occult cause of paraneoplastic acanthosis nigricans in a patient with known breast dcis: case and review

  • B. D. Jakubovic Faculty of Medicine, University of Toronto, Toronto, ON.
  • H. F. Sawires Division of General Surgery & Surgical Oncology, Toronto East General Hospital, University of Toronto, Toronto, ON.
  • D. N. Adam Department of Medicine, Division of Dermatology, St. Michael’s Hospital, University of Toronto, Toronto, ON.

Abstract

Paraneoplastic acanthosis nigricans (PAN) is an infrequently encountered cutaneous manifestation of internal malignancy. Here, we describe a case of PAN in the setting of a known breast ductal carcinoma in situ, which, to our knowledge, had not been described in association with PAN. As a result, thorough investigation was undertaken to search for another concurrent neoplasm that would better explain the development of PAN. In so doing, we identified a coexisting metastatic cholangiocarcinoma. We thus conclude that when pan is observed in an uncommon association with a known malignancy, further investigation should be undertaken to explore whether a more likely occult culprit exists.


How to Cite
Jakubovic, B. D., Sawires, H. F., & Adam, D. N. (1). Occult cause of paraneoplastic acanthosis nigricans in a patient with known breast dcis: case and review. Current Oncology, 19(4), e299-302. https://doi.org/10.3747/co.19.997
Section
Case Report